KMID : 1123920090230040883
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Korean Journal of Oriental Physiology and Pathology 2009 Volume.23 No. 4 p.883 ~ p.887
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Effect of Sacchromyces cerevisiae-Fermented Artemisiae Argi Folium on Nitric oxide Production of Macrophage Treated with Toxicants
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Park Wan-Su
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Abstract
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The effects of Sacchromyces cerevisiae-Fermented Artemisiae Argi Folium Water extract (AFS) on Nitric oxide production from mouse macrophage Raw 264.7 cells treated with EtOH, gallic acid, Nicotine, Acetaminophen, and Acetaldehyde were investigated through this study. AFS (0, 10, 50, 100, 200, 400 ug/mL) was simultaneously treated with EtOH (100 uM), gallic acid (100 uM), Nicotine (1 mM), Acetaminophen (2 mM), and Acetaldehyde (200 uM). And Nitric oxide production from Raw 264.7 cells was measured by Griess reagent method. AFS restorated the cellular production of Nitric oxide reduced by EtOH, gallic acid, Nicotine, and Acetaminophen in Raw 264.7 cells. AFS could be supposed to have the immuno-modulating activity concerned with macrophage¡¯s production of Nitric oxide.
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KEYWORD
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macrophage, Sacchromyces cerevisiae, artemisiae argi folium, fermentation, nitric oxide
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